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ReDRUG algorithm
Restoration using DRug for targeting Unbalanced Gene
Prediction of effect complementation (anti-symmetricity) of drug and disease using transcriptome
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Database
Database with hundreds of disease cohorts and tens of thousands of chemical data
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ONCO 3D scoring system
Accurate gene expression alteration scoring system for drug or disease, using various metrics
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Drug-disease comparison
Scoring anti-symmetricity of diseases and drugs using various algorithms, and integrating them to search optimal disease or drug.
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Cell-tissue similarity-based fine-tuning
Scoring anti-symmetricity with integrating various cell line-based experimental results via cell-tissue similarity. Cell-tissue similarity-based integration method is necessary for accurate prediction, as drug effect data are derived by cell line and disease effect data are from human tissue.
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Combinatorial drug screening
Prediction of the best synergetic effect of two drugs and searching the optimal combinatorial ratio.
Technology
Oncocross AI platform identifies the optimal disease indications and drugs.
